Breast Screening

Regional variation in OBSP coverage, by LHIN, women aged 50-69, 2007 and 2008-2009

Coverage
Target South West 95% CI OBSP 95% CI
Women screened (n)
  61,212   636,511  
Participation rate (%)
≥ 70% 52.2 51.8-52.6 42.0 41.9-42.1
Retention rate* (%)
initial screens ≥ 75% 78.3 77.4-79.2 77.3 77.1-77.6
rescreens ≥ 90% 90.1 89.7-90.5 88.3 88.2-88.5
Participation Rate - The percentage of screen-eligible Ontario women (50-69 years old) who have completed at least one screen in the OBSP in a two-year time period.
Retention Rate - The percentage of screen-eligible women who were rescreened within 30 months of their previous program screen for initial and subsequent screens.
Data Source: Integrated Client Management System, 2010
* Retention rate for women screened in 2007

Regional variation in OBSP follow-up, by LHIN, women aged 50-69, 2008

Follow-Up
Target South West 95% CI OBSP 95% CI
All screens (n)
initial screens   7,718   101,785  
rescreens   28,612   260,783  
Abnormal screens (n)
initial screens   1,375   12,769  
rescreens   2,166   18,130  
Abnormal call rate (%)
initial screens < 10% 17.8 16.9-18.8 12.5 12.3-12.8
rescreens < 5% 7.6 7.3-7.9 7.0 6.9-7.1
Diagnostic interval (%) (%)
within 5 weeks without a tissue biopsy
≥ 90% 66.6 63.8-69.6 81.1 80.0-82.2
within 7 weeks with a tissue biopsy
≥ 90% 51.0 44.9-57.6 55.7 53.5-58.0
Abnormal Call Rate - The percentage of screens that are referred for further testing because of an abnormal result for initial and subsequent screens.
Diagnostic interval (%) - Duration (in weeks) from abnormal screen to diagnosis (benign or cancer) for initial and subsequent program screens combined.
Data Source: Integrated Client Management System, 2010

Regional variation in OBSP quality of screening, by LHIN, women aged 50-69, 2007 and 2008

Quality of Screening
Target South West 95% CI OBSP 95% CI
Abnormal screens (n)
initial screens   1,354   12,484  
rescreens   2,142   17,860  
Breast cancers (n)
initial screens   60   580  
rescreens   127   1,098  
Positive predictive value* (%)
initial screens ≥ 5% 4.4 3.4-5.7 4.6 4.3-5.0
rescreens ≥ 6% 5.9 4.9-7.1 6.1 5.8-6.5
One-year sensitivity** (%)
  90.1 77.4-100 88.1 83.8-92.6
One-year specificity** (%)
  91.2 90.1-92.2 92.2 91.9-92.6
Positive Predictive Value - The percentage of abnormal cases with completed follow-up found to have breast cancer (ductal carcinoma in situ [DCIS] or invasive) after diagnostic work-up for initial and subsequent program screens.
Sensitivity -The proportion of women diagnosed with a screen-detected DCIS and/or invasive breast cancer following completion of diagnostic assessment who had a positive screening test for breast cancer (for initial and subsequent program screens combined).
Specificity - The proportion of women without a diagnosis of DCIS and/or invasive breast cancer who had a negative screening test for breast cancer (for initial and subsequent program screens combined).
Data Source: Integrated Client Management System, 2010
Upper confidence limit was set to a maximum of 100
* Positive predictive values for women screened in 2008      ** Sensitivity and Specificity for women screened in 2007

Regional variation in OBSP detection, by LHIN, women aged 50-69, 2008

Detection
Target South West 95% CI OBSP 95% CI
All screens minus those screens with final results unknown (n)
initial screens   7,697   101,500  
rescreens   28,588   260,513  
Breast cancers (n)
in situ initial   11   92  
in situ rescreens   23   182  
invasive initial   49   488  
invasive rescreens   104   916  
In situ cancer detection rate (per 1,000 screens)
initial screens   1.4 0.7-2.6 0.9 0.7-1.1
rescreens   0.8 0.5-1.2 0.7 0.6-0.8
Invasive breast cancer detection rate (per 1,000 screens)
initial screens > 5  6.4 4.7-8.4 4.8 4.4-5.3
rescreens > 3 3.6 3.0-4.4 3.5 3.3-3.8
In Situ Breast Cancer Detection Rate - The number of women detected with DCIS breast cancer during a screening episode per 1,000 women screened for initial and subsequent program screens.
Invasive Breast Cancer Detection Rate - The number of women detected with invasive breast cancer during a screening episode per 1,000 women screened for initial and subsequent program screens.
Data Source: Integrated Client Management System, 2010

Regional variation in OBSP disease extent at diagnosis, by LHIN, women aged 50-69, 2008

Disease Extent at Diagnosis
South West 95% CI OBSP 95% CI
Invasive breast cancers with known TNM stage group (n)
143   1,218  
Stage I invasive breast cancer (%)
55.2 43.7-68.9 62.2 57.9-66.8
Early Stage Invasive Breast Cancer Detection Rate - The percentage of invasive screen-detected breast cancers detected at an early stage (TNM stage I) for initial and subsequent program screens combined.
Data Source: Integrated Client Management System, 2010